The Kansas City Royals defeated the Boston Red Sox 7-1 on opening day. Gil Meche pitched 7 1/3 innings to pick up the victory. Mark Grudzielanek went 3 for 5 with 3 RBIs. Tony Pena Jr. had 2 triples in his Royals debut. John Buck added a solo shot for Kansas City.

The Royals host the Red sox for 2 more games on the 4th and 5th.